El Imperio del Dolor: La Historia secreta de la dinastía que reinó en la industria farmacéutica

El Imperio del Dolor: La Historia secreta de la dinastía que reinó en la industria farmacéutica

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  • Type:Epub+TxT+PDF+Mobi
  • Create Date:2021-09-24 02:50:59
  • Update Date:2025-09-07
  • Status:finish
  • Author:Patrick Radden Keefe
  • ISBN:841805249X
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Summary

El retrato demoledor de una dinastía cuya fortuna se construyó gracias a Valium y cuya reputación fue destruida por OxyContin。

El imperio del dolor empieza en la Gran Depresión, con la historia de tres hermanos dedicados a la medicina: Raymond, Mortimer y el infatigable Arthur Sackler, dotado de una visión especial para la publicidad y el marketing。 Años después, contribuyó a la primera fortuna familiar ideando la estrategia comercial de Valium, un revolucionario tranquilizante, para una gran farmacéutica。

Con el paso de las generaciones, el apellido Sackler adorna los muros de las instituciones más distinguidas: Harvard, el Metropolitan, Oxford, el Louvre。 Es una de las familias más ricas del mundo, benefactora de las artes y las ciencias。 El origen de su patrimonio siempre fue dudoso, hasta que salió a la luz que lo habían multiplicado gracias a OxyContin, un potente analgésico que catalizó la crisis de los opioides en Estados Unidos。

Tras unas décadas fue Richard Sackler, el hijo de Raymond, quien pasó a dirigir los negocios del clan, incluida Purdue Pharma, su propia empresa fabricante de medicamentos。 Basándose en las tácticas agresivas de su tío Arthur para vender el Valium, lanzó un fármaco que había de ser definitivo: OxyContin。 Con él ganaron miles de millones de dólares, pero terminaría por arruinar su reputación。

Desde 2017, Patrick Radden Keefe ha investigado los secretos de la dinastía Sackler: las complicadas relaciones familiares, los flujos de dinero, sus dudosas prácticas corporativas# El resultado es una bomba periodística que relata el auge y declive de una de las grandes familias americanas y su oscuro emporio de la salud。

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Reviews

Mark Field

Warning: This book is highly addictive reading, you will experience withdrawals。In 2007 when I had the opportunity to visit the Met Museum in New York I marvelled at the Temple of Dendur and reflected on how the wealth of America had acquired the treasures of humanity and neatly housed it all within the museum's walls。 I knew nothing of the Sackler family but it's hard not to be impressed by such generosity of the elite in their gifts to such institutions。I'd been captivated by Radden Keefe's po Warning: This book is highly addictive reading, you will experience withdrawals。In 2007 when I had the opportunity to visit the Met Museum in New York I marvelled at the Temple of Dendur and reflected on how the wealth of America had acquired the treasures of humanity and neatly housed it all within the museum's walls。 I knew nothing of the Sackler family but it's hard not to be impressed by such generosity of the elite in their gifts to such institutions。I'd been captivated by Radden Keefe's podcast "Winds of Change" during the initial Covid-19 lockdown last year and actively checked out his work and listened to interviews with him, so eagerly, and patiently (I was third in the queue) awaited this book to become available from my local library。It's a weighty tome, but one that is fully engrossing, reading like a fast paced thriller, a real page turner。 Radden Keefe's investigation is meticulous and finely detailed, yet you're not bogged down in it。 In the book's afterward he writes, "My intention was to tell a different kind of story, however, a saga of a family dynasty and the ways in which it changed the world, a story about ambition, philanthropy, crime and impunity, the corruption of institutions, power, and greed。" (p437) Of which he does!Lloyd Green's review in the Guardian (18 April 21) states "His secret history of the Sackler Dynasty lays bare the price exacted by the family's for wealth and social mountaineering。" Which succinctly sums it up, yet the family's "。。。indifference and smugness rise off the pages like steam from a sewer。"To me, that is the most astonishing side of this story, the Sacklers' failure to publicly acknowledge their culpability in the devastation of hundreds of thousands of people's lives。 No amount of philanthropic giving can ever mitigate that。Like a great HBO series, this read like Mad Men and The Soprano's begets Succession and The Wire。This is narrative non fiction at its best, crucial, essential and urgent。 。。。more

Zach Eagle

Excellent biography of the Spackler dynasty。 This book is a very detailed and well researched look into the family that paved the way for the opioid addiction epidemic。

Emily Anderson

must read or listen to

Jill

4。25 stars

Debbie Keller

I love it when a nonfiction books reads like a novel! This is the true story of the Sackler family, owners of Purdue Pharma (creators of oxycontin)。 It begins with the story of 3 brothers - Arthur, Raymond, and Mortimer Sackler - who built a fortune selling opioids to Americans and getting many of them hooked on the drugs。 The ability of this family to refuse to see their part in the opioid crisis is frustrating, but more frustrating for me was watching people (lawyers, judges, politicians, etc。 I love it when a nonfiction books reads like a novel! This is the true story of the Sackler family, owners of Purdue Pharma (creators of oxycontin)。 It begins with the story of 3 brothers - Arthur, Raymond, and Mortimer Sackler - who built a fortune selling opioids to Americans and getting many of them hooked on the drugs。 The ability of this family to refuse to see their part in the opioid crisis is frustrating, but more frustrating for me was watching people (lawyers, judges, politicians, etc。)。 bend over backwards to help them avoid any kind of reckoning for their actions。 It's a great book。 。。。more

Krissa

4。5 very well done。

User3729272

reading this made me physically unwell

Jess

One of the best books I've read in recent years。 Highly recommended for anyone interested in the pharmaceutical industry, regulatory capture, the opioid crisis, or the legal case(s) involving the Sacklers。 One of the best books I've read in recent years。 Highly recommended for anyone interested in the pharmaceutical industry, regulatory capture, the opioid crisis, or the legal case(s) involving the Sacklers。 。。。more

Aimala123

Great book。 Full of such interesting facts。 Keefe made it easy to follow the trail of the Sackler legacy, he made a very complicated story accessible to all of us。I would recommend this to anyone who has an interest in the nightmare of the oxycontin crisis。

Mary

PRK has done it again! A tight, thorough account of how the Sacklers built up their inscrutable shield of companies and blamed individuals instead of systems/themselves for the social ills they knowingly created (how convenient)。 Quite detailed and somehow not repetitive or dry in the least。

Libby

Patrick Radden Keefe writes incredibly gripping and compelling nonfiction and Empire of Pain is no exception。 Unless you've been living under a rock the past few years, Purdue Pharma at the very least has probably crossed your news feed。 And it's hard not to kind of hate them a little bit just by reading headlines。 But Purdue and the Sackler family behind the company are truly the scum of the earth。 It's hard not to be shocked by the things these people did to make money and the complete lack of Patrick Radden Keefe writes incredibly gripping and compelling nonfiction and Empire of Pain is no exception。 Unless you've been living under a rock the past few years, Purdue Pharma at the very least has probably crossed your news feed。 And it's hard not to kind of hate them a little bit just by reading headlines。 But Purdue and the Sackler family behind the company are truly the scum of the earth。 It's hard not to be shocked by the things these people did to make money and the complete lack of remorse they have and the lack of responsibility they've taken。 Talk about victim blaming at its very best。 Or worst? Furthermore, how politicians, the FDA, the legal system, and the media have been completely complicit in moving the opioid crisis along。 Plus, the museums, educational institutions, and other non-profits who continued to take their literal blood money year after year, with no crisis of conscience。 Whew。 This book is a deep dive into the Sackler family。 Keefe doesn't go into a lot of the specifics of the opioid crisis - he leaves that for the other books, which he cites frequently, but instead details the Sacklers。 It's very, very good。 But also very, very frustrating。 。。。more

Elena Varipatis

Holy cow, this is a fabulous and fascinating read。 It is so thoroughly researched and provides a ton of history and context。 I hadn’t paid much attention to the ongoing court case regarding the Purdue Pharma bankruptcy, but I will now。As a related aside, it strikes me again and again that, when one has become entangled in a massive crisis, empathy and the admission of wrong-doing are healing and cathartic in and of themselves。 The Sacklers would have done better to do that 10 or 20 years ago tha Holy cow, this is a fabulous and fascinating read。 It is so thoroughly researched and provides a ton of history and context。 I hadn’t paid much attention to the ongoing court case regarding the Purdue Pharma bankruptcy, but I will now。As a related aside, it strikes me again and again that, when one has become entangled in a massive crisis, empathy and the admission of wrong-doing are healing and cathartic in and of themselves。 The Sacklers would have done better to do that 10 or 20 years ago than come off as the tone-deaf and out of touch people that they are showing themselves to be。 。。。more

Timothy Wright

Equal parts fascinating and horrifying story behind the family run business Purdue Pharma and it's role as tip of the spear fueling the opioid epidemic。 Equal parts fascinating and horrifying story behind the family run business Purdue Pharma and it's role as tip of the spear fueling the opioid epidemic。 。。。more

kevin

This is a good book。 Another story about how money and power can corrupt our system。 A fascinating look at the opioid crisis。

Glenda

Read only if you are willing to be even more pissed off at the rich, powerful, and selfish children(aka the sacklers of the world)。

Mary Neupert ohlms

This would be a 4。5 for me。 The book was excellent and well-written。 The Sackler family, on the other hand, is reprehensible。

Jack Graham

Phenomenal and disturbing investigation。 Vital for understanding the opioid crisis。

Sara

eat the rich!!!!!

Cait Morley

Part 1 / 2 are worth a read, Part 3 felt like an extended afterword。。。

Sheryl

Very interesting and knowledgable read

Manuela

Wow。。。La investigación detrás de este libro es TODO。 Es un ejercicio de "periodismo" y no ficción tan, pero tan impecable que parecería ser una ficción。 El tema y las tramas que se elucubran ayudan a que parezca la historia de una saga familiar de tres generaciones colmada de codicia, buscando el provecho propio, a base de la destrucción de todos los demás。 Una familia que se jactó siempre de su "buen nombre" y de sus inmesas donaciones y actividades filantrópicas por todo el mundo, escondían un Wow。。。La investigación detrás de este libro es TODO。 Es un ejercicio de "periodismo" y no ficción tan, pero tan impecable que parecería ser una ficción。 El tema y las tramas que se elucubran ayudan a que parezca la historia de una saga familiar de tres generaciones colmada de codicia, buscando el provecho propio, a base de la destrucción de todos los demás。 Una familia que se jactó siempre de su "buen nombre" y de sus inmesas donaciones y actividades filantrópicas por todo el mundo, escondían un secreto un tanto grande: una de sus "empresitas" fue la que fabricó, comercializó a gran escala (como si de coca cola se tratara) una de las drogas de consumo clínico más poderosas que conoció EEUU: Oxycontin。 Si no la conocen, es cuestión de googlear y se van a dar de lleno con los estragos que causó。 Lo interesante también es que el libro se terminó de escribir casi que ayer, y el caso vs la familia Sackler sigue en juego aún, por ende es un tema de actualidad。 En fin, el libro lo fui escuchando via audiolibro en mucho tiempo y de ratos apabulla la cantidad de información que tiene, pero creo que esto más que nada es mérito del escritor, que logra componer una obra magistral de investigación con un estilo de escritura sólido, impecable。 。。。more

Ren (A Bookish Balance)

4。5/5 starsIncredibly informative and well researched, and pretty digestible considering how much information was given。

James Gross

I do not agree with the authors point of view。 I think its great that this family was so successful in business and helped medicine with the creation of oxycotin。 Just because people are idiots and get hooked to the drug, why blame the manufacturer? I would re-name the title to Empire of entrepreneurs :Sell the pills and make money

Eric

As many of us have become more or less inured to the types of corporate and moral malfeasance Keene writes about in his book about the Sacklers, Purdue Pharma, and the U。S。 opioid crisis, there’s still plenty here to astonish, anger, and frustrate。

Theresa Gienapp

I found this book fascinating and completely disturbing and horrifying。 Well written, at times reads like fiction, but sadly is all true。 The Sacklers have come up repeatedly in my planned giving circles with universities bearing their name on buildings, schools, galleries。

Nick Spacek

superb research, just enough editorializing to keep things in perspective, and maybe the scariest and most depressing book i've read in a minute。 it's certainly no joy to read what the sacklers did and how they responded to the victims of their pharmaceutical ravages, but keefe's writing is a joy to behold, making sense of a thousand intermingling threads in a clear and effective manner, which still conveying the importance of what he's discussing。 superb research, just enough editorializing to keep things in perspective, and maybe the scariest and most depressing book i've read in a minute。 it's certainly no joy to read what the sacklers did and how they responded to the victims of their pharmaceutical ravages, but keefe's writing is a joy to behold, making sense of a thousand intermingling threads in a clear and effective manner, which still conveying the importance of what he's discussing。 。。。more

Mulambo Dorchester

This is an excellent, disturbing and necessary book。 The tragedy of opioid addiction in the USA and its denouement sadly seems to confirm the old saying that "the law is like a spider web: the weak get ensnared in it, while the mighty are too strong and break through it。" The Sacklers and their corporate and government acolytes caused pain, misery and death on an industrial scale, and this book details how that came about。 They may have to fork over a lot of money in various settlements, but the This is an excellent, disturbing and necessary book。 The tragedy of opioid addiction in the USA and its denouement sadly seems to confirm the old saying that "the law is like a spider web: the weak get ensnared in it, while the mighty are too strong and break through it。" The Sacklers and their corporate and government acolytes caused pain, misery and death on an industrial scale, and this book details how that came about。 They may have to fork over a lot of money in various settlements, but they will left with enough to take care of several generations of Sacklers to come, while their victims are either dead or suffer on horifically。 Radden Keefe is detailed, unsparing and blunt in his assessments of those who were behind this disaster and writes in a really accessible style that has enabled me to read this 450+ page book in a matter of days。 If I am being picky, I would have liked to see a family tree, starting with Isaac and Sophie Sackler。 There were a lot of family members and a lot of marriages as well as fathers and sons with the same name, and I had to keep checking back who is related to whom in what way。 Otherwise, however, this is a great piece of investigative journalism and I recommend it thoroughly。 。。。more

Chris

I feel like I understood the Sacklers kind of early on in this tome。 The background of mostly extraneous people started bugging me and I gave up halfway through。

Adrian White

Living the American Dream! Selling a product - and I mean really SELLING! - with no care or obligation for the death and destruction your product brings。 Just like Big Tobacco, just like the NRA, and just like Big Oil。 A terrible tale, well told, that goes way beyond the immediate subject of the Sackler family but which hits the spot with the specific details of that family's greedy pursuit of money and prestige。 They have lost their reputation forever; let's hope that one day they lose all thei Living the American Dream! Selling a product - and I mean really SELLING! - with no care or obligation for the death and destruction your product brings。 Just like Big Tobacco, just like the NRA, and just like Big Oil。 A terrible tale, well told, that goes way beyond the immediate subject of the Sackler family but which hits the spot with the specific details of that family's greedy pursuit of money and prestige。 They have lost their reputation forever; let's hope that one day they lose all their money too and spend the rest of their days incarcerated in the kind of hell they have subjected on so many。 。。。more

Alex C。

The fact that the collapse of this family's empire JUST happened。。。like。。。idk, last year。。。is SHOCKING。The way this family single-handedly ERODED the medical system is CRIMINAL。I really suggest getting this book in audiobook, even listening it at 2。0x speed proved to be a long ride。 However, it was completely worth it。 I have always wondered how our current system with big pharmas started。。。and now I know。 Reading/Listening to this book was like opening up the Pandora's box called: This is Ameri The fact that the collapse of this family's empire JUST happened。。。like。。。idk, last year。。。is SHOCKING。The way this family single-handedly ERODED the medical system is CRIMINAL。I really suggest getting this book in audiobook, even listening it at 2。0x speed proved to be a long ride。 However, it was completely worth it。 I have always wondered how our current system with big pharmas started。。。and now I know。 Reading/Listening to this book was like opening up the Pandora's box called: This is America。 The greed and the complete lack of empathy is jarring; I still can't believe this was allowed to go on for as long as it did (the money helped I bet)。 The worst thing wasn't even that these things happened, the worst thing was that they got away with it, that they did not pay for all lives they disregarded, the misinformation they spread, and the crumbling trust that the American people will never be able to rebuild in their government and healthcare system。 P。S。 I am starting to question a lot of things I was taught in medical school。。。。 。。。more